Two young children died Thursday morning in a fire called out to the Perryville Fire Department, Perryville Police Department and Perry County Sheriff Department at a home in the 700 block of Bruce St. Officers were told by family members who had gotten out of the residence that the two small children remained in the upstairs bedrooms. Officers made attempts to enter the home but were unable to due to the amount of smoke. One child was a boy and the other a girl.An investigation continues.